SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74badbfb46452bb627051cec33fdd156b4384d6ba8a2971face3d6361caaa3cb' 
  AND token = 'WA+huBviRpDbgYvARx+PjZ2vxQcoZqfBBUvlS4t5Qek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}