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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8396a56489c9887b1d2ca0769fec397a42fe382cec4f56a47c2033f4f135b42c' 
  AND token = 'euMbRZ2wPg7J6pcTiI0GKMSLdALsQ6mf/UjUPHdJ70o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}