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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '808dc5393336b9da0ccfb7e2d70b9f76524ced7a444f7b1b31e97e65bc83180a' 
  AND token = 'wm6RWw9iXXfjo3VY8afC2gtezGDjR9ZJcCk8Zhdyaig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}