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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b23a9c1f8a7377e9e2f8d66a87c2c537db8fa89ee16b9e421595ee9078cb7c72' 
  AND token = 'vJ2Jy7FH7Kk+zYZJgrufjXHPjws20f1weAq3R5E2LY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}