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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c7d724b03d0c30f9ffc385175bb185a70c8dffc478bbd6fe1b036e681b5de1' 
  AND token = 'CqF5G3nxAtTLO+4OR0dnOGpKXRQ6n17/TSR9UOJrSrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}