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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0854d70ac114a7f6a3fdd3da8f2d05f2fbafa190ff13da8b5e6fe7ac638aed0' 
  AND token = 'uMJYb6ApTEjCRCB7UdO/5PH4s66CNBEZ+cerY8Uyp2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}