SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca683f4e72be79b634677aa5b646c726cccc4ad8fb8a097d6a540cf1c6355e8b' 
  AND token = 'oM/S5UDs5fPeosnkutk0sjiz3mmVx+UtxLo8l014xvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}