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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a53306a5574f34a378d1046b2c48230d0b1b3b95bb2aaf0046e916478da205f' 
  AND token = 'd+fQEFq4wM3oE3GKmFqvDKUC5RSQPlNDkBI9GfSfgdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}