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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cba45a41362879ee30d77c4fd21105cf4f2fab45c645157b6e3a1a6ee60fd77' 
  AND token = 'ez4GPFli5a1fv6bL3oV7M7DAVyquQcGZTHh3iQ500uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}