SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b047a8031ada99809441a5c76065ae4df164f2831b2601285c06b367043c0489' 
  AND token = 'SICgk/oO0D1XR6EFIyux4xhFfThY1Zq15Gzh4ZXAQeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}