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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f31dccbceb79c4c53f8ba0be5a99fd30d184006ff8e42871d19ebe2730ab1a4' 
  AND token = 'lXv1IG/kaKXtJb4XpWORJZ77g0HUkh8PGWT2Z4ugyf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}