SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af1c67db356ee1332973d3901104af8d61b71fa394a4e68d3ff20c72a4ce0d4' 
  AND token = 'wQ81igHuzouIOWySN9Lu/qelO7HOYQKVFi5XF4xDmAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}