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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8610004d82dd740570c403508b9f1bea3743d5f99a9e7597b9252226c4de44' 
  AND token = 'Ur6w1Iag3685VsMk/Rahv9E5bqjbZGA4NY1r4MU6CUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}