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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28741209cc82a1b03c6bc37f743d49abd9039cf5dc7e9820f8e27b5f44becebe' 
  AND token = 'fd1om7TmMHd347aX+VFV1RtJU5URQwnxKV8aQHyp0lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}