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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385a1b1ded5f1a71ae9ade634beb9e55f0e122d3a8edb9672c82d2e0deb073d5' 
  AND token = 'GqUEqPF1EG1dwXlKOS1PdWa2z3v20N4E/SYOwAdFB7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}