SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc02ef4549e56c4a50a98dbaac7f84cf43ec3dca7e3de3519adcc670ead71354' 
  AND token = 'VxUK4R6hiPbkxSgMuN5iw6Plq2qZCh2WaZV2FGSiYMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}