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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76c2cf6c6bcf3cd7d2601eac4169fbebbc02232236cd11edcc4c2353c1de74e4' 
  AND token = 'QhW1xJfMgoaBKV0PrAe1pRbOtoklMTnwZ9voVhHr4BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}