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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9342787e96b3eb5e890c7c05d3006f341ab6b206b17b2fc4d667e03cdf79cd2c' 
  AND token = 'OzH+pVtcpjW8JBd4BL+aoCYMbRVbtoEgdEuImgKwS18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}