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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adeb38b9b5423f15eab5f1608453851336cd0ebb7930d126629577e21f2c372' 
  AND token = 'nt6rhTUNZObhWgYQIyULjWExOHp53y8PMkEIrlaIq0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}