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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9e80824571bb3b80350ab88ce0fd2da8d680c4841145b3f81884c28b356b3d' 
  AND token = 'PTVvvgrt4LR2bCwSLLYd5sY0rsZbejCql29D2mUdHdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}