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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ce394319783256ca1b460116de8a91afa585868cd19b7a5e9d753f7c486ad8' 
  AND token = 'w+Tj1hN/Xq25k/vkWm061YiU65EI3LZCQ/8d5Gf1fAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}