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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2048745c77c0d44b3030a0a1565f5b596f0115bbdbc43e09e591b0af09e704' 
  AND token = 'JBsO/px121Q6TSZZz4kKtepmBZ5e0tuTXe7uU4t3f7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}