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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782e5a726a1c31ea27dde8aeb9d8dc3dd0cfe66d7621230b4a838225a708df81' 
  AND token = '9eF/pyaOdYTQTsO3J9igDrYAxdQtuLc1lzI9ACkpqvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}