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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ea29453f18335cfb3a9d6cd6b1ff4ce98615f5ba96bfc16aaa6db1e8e11c707' 
  AND token = 'GEE1z6rndYvpRQlqXVs9U5oWfG9uALL7qocRLBwVdGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}