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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affc77ad681a40afafc131a4a8fb50b6be22b4e4f0a36726c1f6700dbb2b3d98' 
  AND token = 'ykhYsYkUjCYxLEA7080iSRVbt4ghnRKTggJ4QRIz/J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}