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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db06e8e2850c1e9f5728f7bb369a9f24056f980529c74c9ad3fedb3702761cd' 
  AND token = 'bfM/TT3Rv7h50KgPuIKUJRh6Lmdi1eePZeu1TIZu2lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}