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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a68a246c6153f0513646b9bd04e39190075fd26389083d016d8f1aa799f5e9' 
  AND token = '2WSxzWPaDj17MW3Xg+FeABVliDx35DF0XfBlBPPXMOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}