SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81f4d736f27c005d4895aa09bb3750198f1aadce37fed018bd5aaa9503173c9' 
  AND token = 'KLBnL+XRbd4aQQmIijHrbWoKkgP6wQQz/xV1zjigtb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}