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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bddcf00a51aa9d954b51882f87852a43fd72f3fc60d12469b5d19018c82873f' 
  AND token = '0JqwMBKxG3acrEszD8N1U6nSZ9PblTFc+x+8BD+YPMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}