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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a937c9d30bf01e66d54b58606886568022cd68a0adc6adea03860a4aac4380' 
  AND token = '7421jZrio+/XnN8MeeoOeqUBLJEiH9ruWBrvvWdl97E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}