SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f7ec3cd2f2a9828971c32d8a85f8116c3b23218d0e0ef2a547f1d919fc5dff' 
  AND token = 'hCtJdDZugTqORlZyBad7rp//Y08Pc/E7UhDZHY+65d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}