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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea493b405d36f5259a6b31f2e8b513397e4a0d9bde4cb81e1e55b5585494fd4' 
  AND token = 'qmlxLKSWALHeeqMtZ/9IXWEATCrNsJR+YeCk/++Yg+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}