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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7638a9dd58d3bcad94c10c6fa1c1f429889cf717ebb2fcc1f25480e60685afe' 
  AND token = 'nlOHzNdsxLZtx1lOtBKw64sXF2/B4JVTtlwknWIE8Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}