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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8562e9c2de2a01c8f5d2ed6f02aa20d05ecde5afa4e01f15f4239707c7af1fa' 
  AND token = 'H6FD2NOvZA+dHYtF241qCKiahx31agsFnLDsM3+7RhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}