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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90a8b8623b8ad33210aa9f8cac31e9c7c27a9332e6d042cd9c6eb741e670a380' 
  AND token = 'gFfrwdFTACgyPzbmnQpIS8YYVBEKmUI/bPXKVqC9RBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}