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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0321fac0a66b6c28972a183336dff97bcd8aacc5ff31ed897f0ee9bf46d2c3fe' 
  AND token = 'rWBqXM1LT8oCHMOVJ8s7tDVPMO5GshkpPsGC1RUdQnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}