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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8b05c778dcf07c84fbd74c8ce999c5e9f11721c4b0b242fdc0615a138d5403' 
  AND token = 'EvuPtx5onMiaoZg0cJbgRFmp9in+n3zwmKHL9lhM5FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}