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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ab5c8372365eb0af95e024d9d41d863a050d97a0e78bccc1825c4b1e05e237' 
  AND token = 'sv4xNRwcIoYEqd9/eha4KBkPSWBWtw9D/1OnXCxKIgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}