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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01868fd0b1161af936241195cd958ec5d130557f7ddbe94a9b6e8bab15c26c8e' 
  AND token = 'he8UrUYJwmTNUDj9fNAFCMkl8PDmxD4g1+gwDr0MHjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}