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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b48c49665329ee67045c2a6e81431ea58da65f3c21e85d792815ff37d9bf1a' 
  AND token = 'Xfe+8TYZINQqd1CSIGU5jhgtK8l3gY5yeVQOUCS2A20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}