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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac864a9dafa5d862f6a98d6799e00212e7d5859137af7af55696cd553f199589' 
  AND token = '2BGo3zH7E/O4G+W/cX/AY1P45PeA3euY3B+3a9mLtbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}