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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748c51cde93d006a552ce813aa43e08fa874c20969153633292dd661768f7f92' 
  AND token = 'C4ya5s5k1Nupl7OLubZj2ZLUV0N6J4GBk6T7Fmd49z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}