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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7d363be02902910bd310de9660a0cd115342a35ac1e1f0bb75f80181b55359' 
  AND token = 'm6WfPhC+8XvSSUW6BwhmGByI4oKtiy+WGeU0b7tte/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}