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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8d6c9912685c16b26887ed3e92bf004b6cc5a27a550bcf4e0d8a7e16f78070' 
  AND token = 'TYsrSE6Fl/4uwWB/b4iy62caEkCSvr1EmDoXDIjjxTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}