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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa804865eff018c22a1f67de65e30fa535defe05c000746d5036e336b5cba27e' 
  AND token = 'pyOb45n33LULuQtoItob1usVa38nMpB1/ZkXklTpOdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}