SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9834db7196385c12af0068ea14af1ab037f70bbae6792b56e5ce5f52ac0017' 
  AND token = 'wBmpiiMWBTHEf14vfD825aM5U0lhW8AiyL+ZhNlXh28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}