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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5e587bb833e03e8435a32b4418b2ba546f3be6b0f317bae54b335b6aced705' 
  AND token = 'jk535h8YN2WJwRmapr9WzEh1ylSG8l2DxKoOzc9JOh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}