SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0efae1ded85134e362c45451e049d1ddf55cdf840e34f8189cfd9760693649d4' 
  AND token = 'Gj+A/4cr9Fb+M02h+3BcBtgvSMDxISTYC/W/Y/6C3ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}