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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d9dea298a28f61c388b904688162c26cb46e20326db7ff95f3547a54f55417' 
  AND token = 'bZ12z8Ru9UqyDiNsYS8DPYHDCm+92cnr5+o4X+C7dSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}