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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0ebc21bfe5b5e0ef2f1d58ca92d92e0dafdd25758034d12da622e6589c3f33' 
  AND token = 'olz56JJ188nf+MDgMeWmRWFyRCPQTtVdpG0ikn0vS0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}